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Opioids relieve pain by sending a flood of dopamine, producing a euphoric high that becomes addictive over time

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(PubMed) Reiter RJ

( Niewiem and Grzybowska-Chlebowczyk, 2022) Eczema & Permeability Pike et al

Leptin signals energy sufficiency to the brain

The intensive early protocol uses injection for maximum initial impact